
The answer to the above question is probably "yes." Of course, you could probably say that about any vitamin or mineral; none of them are "less important" than another.
I interviewed Carol Johnston, a leading vitamin C researcher and a professor at Arizona State University, as part of research for a book I'm writing. She told me about some National Health and Nutrition Examination Survey (NHANES) data from 2004 that showed
31 percent of Americans to be either “scorbutic” (vitamin C blood levels indicating scurvy) or having “marginal vitamin C status” (meaning that “your body tissues are not operating optimally because there is too little of vitamin C there for optimal pathways and metabolism”).
She had me convinced; vitamin C is a
wicked important, underappreciated nutrient. Scurvy is a potentially fatal disease (involving the disintegration of your collagen!), and while the vast majority of people are not getting scurvy, less alarming levels of deficiency cause fatigue, because you're not making enough carnitine.
Vitamin C must be present to produce collagen, the super-strong connective tissue protein in tendons, cartilage, bone, and blood vessels. However,
collagen has an important immune-system role as well, according to Johnston.
“We have defense collagens, little toll-like receptors on immune cells that actually recognize pathogens,” Johnston explained. People who are deficient in vitamin C (up to a third of Americans) have a “marginalized ability to stay infection free.”
Vitamin C is also a
cofactor for making carnitine, a pivotal protein that shuttles fatty acids into the cell’s mitochondria to be burned for energy. “A lot fatigue associated with early marginal C status could be related to carnitine [depletion],” Johnston said, because your metabolic system for using fats energy is compromised.
The fatigue “could [also] be related to norepinephrin,” she said. “No one’s really looked at that” from a scientific research standpoint. Vitamin C is necessary for the production of norepinephrine, which the adrenal glands release as part of the “flight or fight” response. It’s also a neurotransmitter that affects how the heart contracts.
The typical adult stores about 1,500 mg of vitamin C in their body, mostly in the liver and adrenal glands.
What about the
mega doses some people shoot for, such as 40-50 times the RDA for C? “Vitamin C requires a transporter and you can saturate that pretty quickly,” Johnston explained. “When you start taking over 200-500 mg you are really decreasing the amount you can absorb. I don't see a lot of benefit in consuming those high doses if you want to maximize tissue storage. You really need to take small amounts over the course of a day.” For example, 200 mg two or three times per day – if you think you need that dose.
So make sure to chow your oranges, lemons, apples, tomatoes, broccoli (however that idea makes you wince); you need to keep the vitamin C stores up!
The picture, by the way, is of apples I picked yesterday for breakfast (about the extent of my own hunter-gathering). A handful of small apples off a tree are better than one big store-bought apple, because
they tend to have less sugar, and you eat more skin, which increases the antioxidant amounts you are consuming.